Lysosomal Alpha D Mannosidase Deficiency

It is feasible that the primary title of the record Alpha-Mannosidosis is not the name you got. Happy inspect the basic synonyms providing to locate the alternating name(s) and also problem neighborhood(s) covered by this record.


  • alpha-mannosidase B shortage
  • lysosomal alpha-D-mannosidase shortage
  • mannosidase, alpha B, lysosomal
  • mannosidosis
  • mannosidosis, alpha B, lysosomal

Problem Subdivisions

  • alpha-mannosidosis, kind I
  • alpha-mannosidosis, kind II
  • alpha-mannosidosis, kind III

General Discussion
Alpha-mannosidosis is an uncommon hereditary condition defined by a shortage of the enzyme alpha-D-mannosidase. Alpha-mannosidosis is finest idea of as a continuum of condition that is usually damaged down right into 3 types: a moderate, gradually dynamic type (kind 1); a modest type (kind 2); as well as a serious, frequently swiftly modern as well as possibly lethal type (kind 3). The signs and symptoms and also intensity of the problem are very variable.

Alpha-mannosidosis belongs to a team of conditions recognized as the lysosomal storage space problems. Reduced degrees or lack of exercise of the alpha-mannosidase enzyme leads to the unusual build-up of substances upstream in the metabolic path in the cells of damaged people with undesirable repercussions.

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